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Investigating the effect of oil spills
on the environment and public health.
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Daniel Schlenk

University of California Riverside

Department of Environmental Sciences

900 University Avenue
Geology 2258
Riverside, CA  92521  

daniel.schlenk@ucr.edu

Project List:

Relationship of Effects of Cardiac Outcomes in Fish for Validation of Ecological Risk II (RECOVER II)

Year 8-10 Research Grants (RFP-VI)Role: Co-Principal Investigator

Relationship of Effects of Cardiac Outcomes in Fish for Validation of Ecological Risk (RECOVER)

Year 5-7 Consortia Grants (RFP-IV)Role: Task Lead, Co-Principal Investigator

Publications & Presentations:

Journal Articles - 14

2021

McGruer, V., Tanabe, P., Vliet, S. M., Dasgupta, S., Qian, L., Volz, D. C., & Schlenk, D. (2021). Effects of Phenanthrene Exposure on Cholesterol Homeostasis and Cardiotoxicity in Zebrafish Embryos. Environmental Toxicology and Chemistry, 40(6), 1586-1595.

2020

Magnuson, J. T., Bautista, N. M., Lucero, J., Lund, A. K., Xu, E. G., Schlenk, D., Burggren, W. W., & Roberts, A. P. (2020). Exposure to Crude Oil Induces Retinal Apoptosis and Impairs Visual Function in Fish. Environmental Science & Technology, 54(5), 2843-2850.

2019

Greer, J. B., Andrzejczyk, N. E., Mager, E. M., Stieglitz, J. D., Benetti, D., Grosell, M., & Schlenk, D. (2019). Whole-Transcriptome Sequencing of Epidermal Mucus as a Novel Method for Oil Exposure Assessment in Juvenile Mahi-Mahi (<i>Coryphaena hippurus</i>). Environmental Science &amp; Technology Letters, 6(9), 538-544.
Greer, J. B., Pasparakis, C., Stieglitz, J. D., Benetti, D., Grosell, M., & Schlenk, D. (2019). Effects of corexit 9500A and Corexit-crude oil mixtures on transcriptomic pathways and developmental toxicity in early life stage mahi-mahi (Coryphaena hippurus). Aquatic Toxicology, 212, 233-240.
McGruer, V., Pasparakis, C., Grosell, M., Stieglitz, J. D., Benetti, D. D., Greer, J. B., & Schlenk, D. (2019). Deepwater Horizon crude oil exposure alters cholesterol biosynthesis with implications for developmental cardiotoxicity in larval mahi-mahi (Coryphaena hippurus). Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology, 220, 31-35.
Perrichon, P., Stieglitz, J. D., Xu, E. G., Magnuson, J. T., Pasparakis, C., Mager, E. M., Wang, Y., Schlenk, D., Benetti, D. D., Roberts, A. P., Grosell, M., & Burggren, W. W. (2019). Mahi‐mahi (<scp><i>Coryphaena hippurus</i></scp>) life development: morphological, physiological, behavioral and molecular phenotypes. Developmental Dynamics, 248(5), 337-350.
Xu, E. G., Khursigara, A. J., Li, S., Esbaugh, A. J., Dasgupta, S., Volz, D. C., & Schlenk, D. (2019). mRNA-miRNA-Seq Reveals Neuro-Cardio Mechanisms of Crude Oil Toxicity in Red Drum (<i>Sciaenops ocellatus</i>). Environmental Science &amp; Technology, 53(6), 3296-3305.

2017

Diamante, G., do Amaral e Silva Müller, G., Menjivar-Cervantes, N., Xu, E. G., Volz, D. C., Dias Bainy, A. C., & Schlenk, D. (2017). Developmental toxicity of hydroxylated chrysene metabolites in zebrafish embryos. Aquatic Toxicology, 189, 77-86.
Diamante, G., Menjivar-Cervantes, N., Leung, M. S., Volz, D. C., & Schlenk, D. (2017). Contribution of G protein-coupled estrogen receptor 1 (GPER) to 17β-estradiol-induced developmental toxicity in zebrafish. Aquatic Toxicology, 186, 180-187.
Diamante, G., Xu, E. G., Chen, S., Mager, E., Grosell, M., & Schlenk, D. (2017). Differential Expression of MicroRNAs in Embryos and Larvae of Mahi-Mahi (<i>Coryphaena hippurus</i>) Exposed to <i>Deepwater Horizon</i> Oil. Environmental Science &amp; Technology Letters, 4(12), 523-529.
Xu, E. G., Khursigara, A. J., Magnuson, J., Hazard, E. S., Hardiman, G., Esbaugh, A. J., Roberts, A. P., & Schlenk, D. (2017). Larval Red Drum (<i>Sciaenops ocellatus</i>) Sublethal Exposure to Weathered Deepwater Horizon Crude Oil: Developmental and Transcriptomic Consequences. Environmental Science &amp; Technology, 51(17), 10162-10172.
Xu, E. G., Mager, E. M., Grosell, M., Hazard, E. S., Hardiman, G., & Schlenk, D. (2017). Novel transcriptome assembly and comparative toxicity pathway analysis in mahi-mahi (Coryphaena hippurus) embryos and larvae exposed to Deepwater Horizon oil. Scientific Reports, 7(1).
Xu, E. G., Mager, E. M., Grosell, M., Stieglitz, J. D., Hazard, E. S., Hardiman, G., & Schlenk, D. (2017). Developmental transcriptomic analyses for mechanistic insights into critical pathways involved in embryogenesis of pelagic mahi-mahi (Coryphaena hippurus). PLOS ONE, 12(7), e0180454.

2016

Xu, E. G., Mager, E. M., Grosell, M., Pasparakis, C., Schlenker, L. S., Stieglitz, J. D., Benetti, D., Hazard, E., Courtney, S. M., Diamante, G., Freitas, J., Hardiman, G., & Schlenk, D. (2016). Time- and Oil-Dependent Transcriptomic and Physiological Responses to <i>Deepwater Horizon</i> Oil in Mahi-Mahi (<i>Coryphaena hippurus</i>) Embryos and Larvae. Environmental Science &amp; Technology, 50(14), 7842-7851.

Book Chapter - 1

2019

Portnoy, D. S., Fields, A. T., Greer, J. B., & Schlenk, D. (2020). Genetics and Oil: Transcriptomics, Epigenetics, and Population Genomics as Tools to Understand Animal Responses to Exposure Across Different Time Scales. In Murawski, S. A., Ainsworth, C. H., Gilbert, S., Hollander, D. J., Paris, C. B., Schlüter, M., & Wetzel, D. L. (Eds.), Deep Oil Spills (pp. 515-532) Springer International Publishing.

Conference Presentations - 47

2019

Andrzejczyk, N. A., D.; Palace, V. J., D.; Weber, L. S., & D (2019). Whole-transcriptome sequencing of sub-adult fathead minnow liver following water-accommodated conventional heavy crude oil exposure. In SETAC North America 40th Annual Meeting
Andrzejczyk, N. G., J.; Mager, E. G., & M.; Schlenk, D. (2019). Whole-Transcriptome Sequencing of Epidermal Mucus as a Novel Method for Oil Exposure Assessment in Juvenile Mahi-Mahi. In Southern California Regional Chapter of the Society of Environmental Toxicology and Chemistry (SETAC) 2019 Annual Meeting
Andrzejczyk, N. G., J.; Mager, E. G., & M.; Schlenk, D. (2019). Transcriptomic Analysis of Juvenile Mahi-Mahi (Coryphaena hippurus) Dermal Mucus as a Noninvasive Monitoring Tool for Effects of Deepwater Horizon Oil Exposure. In 20th International Symposium on Pollutant Responses In Marine Organisms (PRIMO20)
Bonatesta, F. G., J.; Xu, E. S., & D.; Mager, E. (2019). Effects of Deepwater Horizon Crude Oil Exposure on the Developing Teleost Kidney. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2019
Bonatesta, F. G., J.; Xu, E. S., & D.; Mager, E. (2019). Effects of Deepwater Horizon Crude Oil Exposure on the Developing Teleost Kidney. In South Central Regional Chapter of the Society of Environmental Toxicology and Chemistry (SETAC) 2019 Annual Meeting
Bonatesta, F. K., A.; Greer, J. X., E.; Schlenk, D. E., & A.; Mager, E. (2019). Acute and Latent Effects on the Teleost Kidney Following Early Life-Stage Exposure to Deepwater Horizon Crude Oil. In SETAC North America 40th Annual Meeting
Bonatesta, F. P., E.; Greer, J. X., E.; Schlenk, D. M., & E (2019). Effects of Deepwater Horizon crude oil exposure on the developing teleost kidney. In Society of Experimental Biology 2019 Annual Meeting
Greer, J. D., S.; Volz, D. S., & D (2019). Overabundance of microRNA 133b induces oil-like cardiotoxicity in zebrafish (Danio rerio) embryos. In SETAC North America 40th Annual Meeting
Greer, J. D., S.; Volz, D. S., & D (2019). Overbundance of microRNA 133b induces oil-like cardiotoxicitiy in zebrafish (Danio rerio). In 20th International Symposium on Pollutant Responses In Marine Organisms (PRIMO20)
Greer, J. D., S.; Volz, D. S., & D (2019). Overbundance of microRNA 133b induces oil-like cardiotoxicitiy in zebrafish (Danio rerio). In Southern California Regional Chapter of the Society of Environmental Toxicology and Chemistry (SETAC) 2019 Annual Meeting
Greer, J. P., C.; Stieglitz, J. B., D.D.; Grosell, M. S., & D (2019). Effects of Corexit 9500A-crude oil mixtures on transcriptomic pathways and developmental toxicity in early life stage mahi-mahi (Coryphaena hippurus). In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2019
Greer, J. P., C.; Stieglitz, J. B., D.D.; Grosell, M. S., & D (2019). Toxicity of chemical dispersant and chemically dispersed crude oil in developing mahi embryos. In 20th International Symposium on Pollutant Responses In Marine Organisms (PRIMO20)
Leads, R. M., J.T.; Lucero, J. L., A.; Schlenk, D. C., & R.; Roberts, A. (2019). Incidence of apoptosis in larval red drum co-exposed to crude oil and ultraviolet radiation. In SETAC North America 40th Annual Meeting
McGruer, V. P., C.; Khursigara, A. V., D.C.; Esbaugh, A. G., & M.; Schlenk, D. (2019). Deepwater Horizon oil alters the cholesterol biosynthetic pathway in exposed larval fish. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2019
McGruer, V. V., S.; Dasgupta, S. V., & D.; Schlenk, D. (2019). Phenanthrene Impacts the Cholesterol Biosynthetic Pathway and Cardiac Development in Zebrafish Embryos. In 20th International Symposium on Pollutant Responses In Marine Organisms (PRIMO20)
McGruer, V. V., S.; Dasgupta, S. V., & D.; Schlenk, D. (2019). Crude Oil and PAH Components Impact the Cholesterol Biosynthetic Pathway and Cardiac Development in Fish Embryos. In SETAC North America 40th Annual Meeting
Schlenk, D. (2019). Novel Mechanisms of Action of PAHs on Larval Fish Development. In 6th National Ecotoxicology Conference
Schlenk, D. (2019). Use of microRNA and mRNA analyses to identify novel modes of action of environmental contaminants to. In 9th International Conferences on Marine Pollution and Ecotoxicology
Schlenk, D. (2019). Use of microRNA and mRNA analyses to identify novel modes of action of environmental contaminants to early life stage fish. In 10th National Conference on Environmental Chemistry (NCEC 2019)
Tanabe, P. M., C.; Cheng, V. V., & D.; Schlenk, D. (2019). Regioselective Effects of OxyPAHs on Red Blood Cell Concentrations in Japanese Medaka Embryos. In 20th International Symposium on Pollutant Responses In Marine Organisms (PRIMO20)
Tanabe, P. M., C.; Cheng, V. V., & D.; Schlenk, D. (2019). Regioselective Effects of Oxygenated Polycyclic Aromatic Hydrocarbons on Red Blood Cell Concentrations in Japanese Medaka Embryos. In SETAC North America 40th Annual Meeting

2018

Greer, J. P., C.; Grosell, M. S., & D (2018). Multi-level effects of chemical oil dispersant and CEWAF exposures in developing mahi-mahi embryos. In SETAC North America 39th Annual Meeting
Grosell, M. S., J.D.; Heuer, R. P., C.; Schlenker, L. M., J.T.; Nelson, D. X., E.; Schlenk, D. C., D.A.; Roberts, A. B., & D.D (2018). A wide range of endpoints are impacted by oil exposure in early and later life stages of marine fish. In SETAC Europe 28th Annual Meeting
Magnuson, J. B., E.; Khursigara, A. E., A.; Xu, E. S., D.; Stieglitz, J. H., R.; Grosell, M. R., & A (2018). Early life stage fishes exposed to crude oil have reduced visual development and function. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2018
McGruer, V. P., C.; Khursigara, A. V., S.; Dasgupta, S. V., D.C.; Esbaugh, A. G., & M.; Schlenk, D. (2018). Exploring Mechanisms of Cardiotoxicity in Crude Oil Exposed Fish. In SETAC North America 39th Annual Meeting
Schlenk, D. (2018). microRNA and messenger RNA networks in early life stages of pelagic and nearshore fish species exposed to Deepwater Horizon oil. In SETAC Europe 28th Annual Meeting
Schlenk, D. (2018). Genomic Networks Predict Apical Impairment In Early Life Stages Of Mahi Mahi Exposed To Oil. In ASLO 2018 Summer Meeting
Schlenk, D. X., E.; Diamante, G. C., S.; Mager, E. G., & M (2018). Integration of microRNA and mRNA in early life stages of mahi after exposure to Deepwater Horizon oil. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2018

2017

Diamante, G.; do Amarel e Silva Muller, G.; Menjivar-Cervantes, N. V., D.C.; Dias Bainy, A. S., & D (2017). Developmental toxicity of 2- and 6-hydroxychrysene on zebrafish embryos. In 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO 19)
Grosell, M. C., G.K.; Heuer, R. P., C.; Schlenker, L. S., J.; Roberts, A. M., J.T.; Schlenk, D. X., E.G.; Crossley, D. N., & D.; Benetti, D. (2017). Impacts of crude oil on marine pelagic fish: From molecular and cellular responses to habitat utilization of wild mahi-mahi (Coryphaena hippurus). In SETAC North America 38th Annual Meeting
Magnuson, J. A., E.; Khursigara, A. X., E.G.; Esbaugh, A. S., D.; Stieglitz, J. G., & M.; Roberts, A. (2017). Effects of Deepwater Horizon crude oil on visual function in early life stage fishes. In SETAC North America 38th Annual Meeting
Schlenk, D. (2017). Comparative transcriptomic analysis of mahi-mahi (Coryphaena hippurus) and red drum (Sciaenops ocellatus) embryos and larvae reveals key toxicity pathways in response to Deepwater Horizon oil. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2017
Schlenk, D. (2017). Use of transcriptomic and informatic tools to predict adverse outcome pathways of oil to embryonic and larval fish from the Gulf of Mexico. In 9th National Conference for Environmental Chemistry
Schlenk, D. (2017). Use of transcriptomic and informatic tools to predict adverse outcome pathways of oil to embryonic and larval fish from the Gulf of Mexico. In National Conference for Fisheries and Aquaculture
Sweet, L. B., K.; Pasparakis, C. P., P.; Crossley, J. S., J.; Benetti, D. C., D.A.; Grosell, M. M., K.; Schlenk, D. R., & A (2017). The effects of photoproducts generated from irradiated crude oil exposures on a pelagic fish species, the mahi mahi (Coryphaena hippurus). In 3rd International Conference on Environmental Pollution, Restoration, and Management
Xu, E. D., G.; Chai, S. M., E.M.; Grosell, M. S., & D (2017). Regulation of microRNAs in mahi-mahi (Coryphaena hippurus) exposed to Deepwater Horizon oil. In 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO 19)
Xu, E. D., G.; Chen, S. M., E.; Grosell, M. S., & D (2017). Regulation of microRNAs in mahi-mahi (Coryphaena hippurus) exposed to Deepwater Horizon oil. In SETAC North America 38th Annual Meeting

2016

Diamante, G.; do Amaral e Silva Muller, G.; Celso Dias Bainy, A. S., & D (2016). Effects of 2- and 6-hydroxylated Chrysene on the Development of Danio rerio Embryos. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016
Diamante, G.; do Amaral e Silva Muller, G.; Celso Dias Bainy, A. S., & D (2016). Effects of 2- and 6-hydroxylated Chrysene on the Development of Danio rerio Embryos. In Society of Toxicology 2016 Annual Meeting
Diamante, G. M., G.; Menjivar Cervantes, N. B., A.; Volz, D. S., & D (2016). Developmental toxicity of 2- and 6-hydroxychrysene in zebrafish embryos. In 7th Society of Environmental Toxicology and Chemistry (SETAC) World Congress/SETAC North America 37th Annual Meeting
Diamante, G. M., & G.D.; Bainy A.; Schlenk, D. (2016). Developmental toxicity of 2- and 6-hydroxychrysene on Danio rerio embryos. In Southern California Society of Environmental Toxicology and Chemistry
Muller, G. D., & G.; Bainy A.; Schlenk, D. (2016). Developmental effects of 2 and 6-hydroxychrysene on zebrafish embryos. In Society of Environmental Toxicology and Chemistry Annual Meeting Europe
Sweet, L. S., J.; Morris, J. R., A.; Hook, S. E., A.; Perrichon, P. P., C.; Stieglitz, J. B., D.; Grosell, M. M., K.; Schlenk, D. R., & A.P (2016). The effects of photoproducts generated from irradiated crude oil exposures on pelagic and estuarine fish species. In 7th Society of Environmental Toxicology and Chemistry (SETAC) World Congress/SETAC North America 37th Annual Meeting
Xu, G. K., A.; Starr Hazard, E. H., G.; Esbaugh, A. G., & M.; Schlenk, D. (2016). Global transcriptional responses to Deepwater Horizon oil in red drum (Sciaenops ocellatus) embryos. In 7th Society of Environmental Toxicology and Chemistry (SETAC) World Congress/SETAC North America 37th Annual Meeting
Xu, G. M., E.; Grosell, M. H., E.; Courtney, S. H., & G.; Schlenk, D. (2016). Genome-Wide Transcriptional Responses toDeepwater Horizon Oil in Mahi-Mahi (Coryhaena hippurus)embryos. In Society of Toxicology 2016 Annual Meeting
Xu, G. M., E.; Grosell, M. P., C.; Schlenker, L. S., J.; Benetti, D. H., E.S.; Courtney, S. D., G.; Freitas, J. H., & G.; Schlenk, D. (2016). Time and oil dependent genomic and physiological responses to Deepwater Horizon oil in mahi-mahi (Coryphaena hippurus) embryos. In 7th Society of Environmental Toxicology and Chemistry (SETAC) World Congress/SETAC North America 37th Annual Meeting

2015

Diamante, G. S., & D (2015). Developmental Effects of 2-hydroxychrysene in Zebrafish (Danio Rerio) Embryos. In SETAC North America 36th Annual Meeting