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Investigating the effect of oil spills
on the environment and public health.
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Satomi Kohno

Medical University of South Carolina

Hollings Marine Lab

331 Ft. Johnson Rd.
Charleston, SC  29412  

kohnos@gmail.com

Project List:

Using Embryonic Stem Cell Fate to Determine Potential Adverse Effects of Petroleum/Dispersant Exposure

Year 3-5 Investigator Grants (RFP-II)Role: Co-Principal Investigator

Publications & Presentations:

Journal Articles - 4

2016

McCoy, K. A., Roark, A. M., Boggs, A. S., Bowden, J. A., Cruze, L., Edwards, T. M., Hamlin, H. J., Cantu, T. M., McCoy, J. A., McNabb, N. A., Wenzel, A. G., Williams, C. E., & Kohno, S. (2016). Integrative and comparative reproductive biology: From alligators to xenobiotics. General and Comparative Endocrinology, 238, 23-31.
Toyota, K., McNabb, N. A., Spyropoulos, D. D., Iguchi, T., & Kohno, S. (2017). Toxic effects of chemical dispersant Corexit 9500 on water flea <i>Daphnia magna</i>. Journal of Applied Toxicology, 37(2), 201-206.

2015

Kohno, S., Bernhard, M. C., Katsu, Y., Zhu, J., Bryan, T. A., Doheny, B. M., Iguchi, T., & Guillette, L. J. (2015). Estrogen Receptor 1 (ESR1; ERα), not ESR2 (ERβ), Modulates Estrogen-Induced Sex Reversal in the American Alligator, a Species With Temperature-Dependent Sex Determination. Endocrinology, 156(5), 1887-1899.

2014

Kohno, S., Parrott, B. B., Yatsu, R., Miyagawa, S., Moore, B. C., Iguchi, T., & Guillette Jr., L. (2014). Gonadal Differentiation in Reptiles Exhibiting Environmental Sex Determination. Sexual Development, 8(5), 208-226.

Conference Presentations - 40

2016

Brumbaugh, A. W., C.; Guillette, L. S., & D.D.; Kohno, S. (2016). Obesogenic activity of oil dispersant corexit 9500 in the American alligator. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016
Kohno, S. N., R.B.; Nishizawa, H. G., L.J.; Kitai, T. S., & T (2016). Transgenerational alteration of estrus cycle proportion in F1 female mice obtained from F0 males neonatally exposed to 17?-hydroxyprogesterone caproate. In Annual Meeting of Society for Maternal Fetal Medicine
Kohno, S. P., & B.B (2016). What 12 years of research tells us: Bad environments for wildlife won't be good for humans. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016
McNabb, N. M., S.; Iguchi, T. S., D.D.; Guillette, L. K., & S (2016). Investigating estrogenicity of oil dispersant COREXIT® EC9500A in the American alligator and diamondback terrapin. In Annual Meeting of Society for Maternal Fetal Medicine
McNabb, N. S., D.D.; Guillette, L. K., & S (2016). Investigating estrogenicity and developmental effects of the dispersant COREXIT® EC9500A in the American alligator. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016
McNabb, N. S., D.D.; Guillette, L. K., & S (2016). Investigating Estrogenicity Of COREXIT In The American Alligator: Learning In The Field And Lab From Lou Guillette. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016
McNabb, N. W., C.E.; Spyropoulos, D. G., & L.J.; Kohno, S. (2016). Investigating effects of COREXIT and CWAF on sex determination in the American alligator. In Palmetto Alligator Research and Management Symposium.
Spyropoulos, D. T., A.M.; Cantu, T. M., N.A.; Williams, C. B., R.R.; Bowden, J. K., J.R.; Kohno, S. B., & J.E.; Guillette, L. (2016). From Oiled Stem Cells to Pregnant Women: Methodically Navigating Between Complex Environments and Human Health. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016
Williams, C. G., L.J.; Spyropoulos, D. K., & S (2016). Estrogenic effects of CWAF exposure on sex determination in the American alligator. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016
Williams, C. G., L.J.; Spyropoulos, D. K., & S (2016). Effects of exogenous estradiol on gonadal sex determination in the American alligator during in vitro culture of the isolated gonad-adrenal-mesonephric complex. In Annual Meeting of the Society for Integrative and Comparative Biology
Williams, C. S., D.D.; Guillette, L. K., & S (2016). Lessons in research and beyond from Lou Guillette - assessing the impacts of CWAF on sex determination in the American alligator. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2016

2015

Bernhard, M. S., D.D.; Guillette, L. K., & S (2015). Can tributyltin be used as a positive control for obesogenic exposure in the American alligator (Alligator mississippiensis)?. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2015
Brumbaugh, A. S., & D.D.; Kohno, S. (2015). Obesogenic Activity of Oil Dispersant Components in the American Alligator Following the Deepwater Horizon Oil Spill. In 2015 Medical University of South Carolina, HML Poster Session of the Summer Undergraduate Research Program: Endocrine Disrupting Compounds, the Environment and Human Health.
Brumbaugh, A. S., & D.D.; Kohno, S. (2015). Obesogenic Activity of Oil Dispersant Components in the American Alligator Following the Deepwater Horizon Oil Spill. In 2015 Medical University of South Carolina Summer Undergraduate Research Program Oral Presentations
Kitai, T. N., H.; Iguchi, T. G., L.J.; Kohno, S. S., & T (2015). Reproductive study of f1 mice obtained from F0 mice neonatally exposed to 17?-hydroxyprogesterone caproate. In 63rd NIBB Conference: Environment to Bioresponse
Kohno, S. M., N.A.; Williams, C. S., D.D.; Guillette, L. P., & B.B (2015). Long-term influences of environmental factors on sex determination and differentiation in the American alligator. In 63rd NIBB Conference: Environment to Bioresponse
McNabb, N. S., D.D.; Guillette, L. K., & S (2015). Effects Of COREXIT 9500 As A Potential Endocrine Disruptor On Sex Determination Of The American Alligator. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2015
McNabb, N. G., L.J.; Spyropoulos, D. K., & S (2015). Investigating estrogenicity and developmental effects of the dispersant COREXIT in the American alligator and diamondback terrapin. In 19th Annual College of Charleston Graduate Program in Marine Biology Student Research Colloquium
McNabb, N. M., S.; Iguchi, T. S., D.D.; Guillette, L. K., & S (2015). Investigating estrogenicity and developmental effects of the dispersant COREXIT in the American alligator and diamondback terrapin. In 63rd NIBB Conference: Environment to Bioresponse
Temkin, A. B., R.; Baatz, J. G., L.J.; Kohno, S. S., & D.D (2015). Keynote Speaker: Empowering Awareness of Environmental Impacts on Women's Health - From Wildlife and Stem Cells to the Clinic and Personal Choices. In Carolina Women’s Health Research Forum
Williams, C. G., L.J.; Spyropoulos, D. K., & S (2015). Estrogenic Effects Of CWAF Exposure In Vitro On Sex Determination Of The American Alligator. In 19th Annual College of Charleston Graduate Program in Marine Biology Student Research Colloquium

2014

Barrett, N. T., A.; Ellisor, D. K., S.; Guillette, L., & ; Spyropoulos, D. (2014). Histological Analysis of Adipose Tissue in the Tail of American Aliigators Exposed to Tributyltin in ovo. In MUSC Marine Biomedicine & Environmental Sciences Program, Summer Undergraduate Research Program Student Colloquium
Barrett, N. T., A.; Kohno, S. G., L.J, ;. S., & D.D (2014). Histological Analysis of Adipose Tissue in the Tail of American Aliigators Exposed to Tributyltin in ovo. In Summer Undergraduate Research Program, Final Presentation Day
Bernhard, M. K., S.; Guillette, L., & ; Spyropoulos, D. (2014). Effects Of Ppar?/Rxr? Signaling Via In Ovo Tributyltin Exposure On Development Of The American Alligator, Alligator Mississippiensis. In College of Charleston Marine Biology Graduate Program Student Research Colloquium 2014
Bernhard, M. S., & D.D.; Guillette L. J.; Kohno, S. (2014). Does in ovo exposure to a known endocrine disruptor, tributyltin (TBT), skew sex ratios in the American alligator (Alligator mississippiensis)-. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2014
Bowden, J. W., M.; Kohno, S. S., & T (2014). Development of a multi-omics approach using a single extraction. In ASMS Conference on Mass Spectrometry and Allied Topics - 62nd
Cloy-McCoy, J. K., & S.; Guillette Jr, L. (2014). The influence of environmental quality on ovarian anti-Mu-llerian hormone (AMH) gene expression in juvenile American alligators. In 2014 Annual Meeting of SICB
Doheny, B. K., S.; Cloy-Mccoy, J. G. J., & L.J (2014). Receptor Isoform-specific Estrogen Signaling in Mu-llerian Duct Differentiation of the American Alligator. In 2014 Annual Meeting of SICB
Guilette, L. P., B.B.; McCoy, J. B., & J.A.; Kohno, S. (2014). Environmental contaminants and sex determination/gonadal differentiation in a wildlife sentinel species: Gene expression and epigenetic regulation of gonadal development. In 8th International Symposium on Amphibian and Reptilian Endocrinology and Neurobiology
Guillette, L. P., B.; Bowden, J. K., & S (2014). Endocrine Disrupting Contaminants and the Developing Reproductive System. In Society for the Study of Reproduction 2014 ; Fertility: A Global Challenge
Kohno, S. B., M.C.; Barrett, N. M., & N.B.; Guilette, L. (2014). American alligator: A sentinel species for developmental effects of endocrine disrupting compounds. In 8th International Symposium on Amphibian and Reptilian Endocrinology and Neurobiology
Kohno, S. G. J., & L.J (2014). Association of mRNA abundance for various steroid hormone related factors in circulating blood cells with plasma chemical -components during the stress response in the American alligator. In 2014 Annual Meeting of SICB
Kohno, S. S., T.; Miyagawa, S. N., R.; Iguchi, T. G., & L.J (2014). Neonatal exposure to a synthetic progestin, 17?-hydroxyprogesterone caproate suppressed estrogenic responsiveness in transcriptome of female reproductive tract in adult mice. In Gordon Research Conferences, Mammalian Reproduction
McNabb, N. K., & S.; Guillette, L. (2014). Effects of COREXIT 9500 As A Potential Endocrine Disruptor On Sex Determination Of The American Alligator. In College of Charleston Marine Biology Graduate Program Student Research Colloquium 2015
Parrott, B. K., S.; Cloy-Mccoy, J. G., & J, L. (2014). Gonadal DNA methylation patterning is affected by incubation temperature in the American alligator, a species undergoing temperature-dependent sex determination. In 2014 Annual Meeting of SICB
Patton, M. T., A.; Ellisor, D. K., S.; Guillette, L., & ; Spyropoulos, D. (2014). Using Molecular Markers to Rapidly Characterize Adipogenic Stem Cell Differentiation. In 2014 Annual Meeting of SICB
Schock, T. W., M.; Kohno, S. B., & J.A (2014). An integrated omics extraction protocol for maximum recovery of biological information from a single sample. In International Conference of the Metabolomics Society - 10th Anniversary
Temkin, A. B., R.; Ellisor, D. B., J.E.; Kucklick, J. K., & S.; Guillette L. J.; Spyropoulos, D. (2014). Predicting Long Term Impacts of MC252 Oil/COREXIT Exposures on Human Health and Higher Trophic Organisms: Obesogenicity. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2014

2013

Ellisor, D. C., J.A, C., T.M.; Kohno, S. B., J.E.; Guillette, L. S., & D.D (2013). Using Embryonic Stem Cell Fate to Determine Potential Adverse Effects of Petroleum/Dispersant Exposure. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2013
Ellisor, D. C., J.A, C., T.M.; Kohno, S. B., J.E.; Guillette, L. S., & D.D (2013). Using Embryonic Stem Cell Fate to Determine Potential Adverse Effects of Petroleum/Dispersant Exposure. In Gulf of Mexico Oil Spill & Ecosystem Science Conference 2013